Strongly Magnetic Iron/Iron Oxide Core-Shell Nanoparticles
At Boutiq, we have pioneered a novel synthesis for unique iron-iron oxide core-shell nanoparticles which exhibit strong magnetic behaviour. Most current magnetic nanoparticles use iron oxides, which show weaker magnetic behaviour than pure iron.
In comparison, the magnetisation of our Fe-FeOx NPs is up to 150 emug-1, which is at least double the 40-70 emug-1 reported for commercially available iron oxide. In addition, our Fe-FeOx nanoparticles are uniformly sized and are near ‘superparamagnetic’: with a small to zero coercivity they only show magnetic behaviour in a magnetic field.
As they can be made biocompatible with surface modification, they are ideal candidates for applications in MRI, drug delivery and magnetic hyperthermia. Please see our publications on these materials, including our research on application in MRI: where a T2 relaxivity of double current iron oxides results in improved negative contrast, specificity and sensitivity.
Example Specification Sheet
- Material: Iron-Iron Oxide (Fe-FeOx) Core-Shell. Consists of iron metal (Fe) core with layer of iron oxide spinel shell.
- Size: 10 to 15 nm
- Standard deviation: < 3 nm
- Shape: Spherical to near-cubic
- Physical appearance: black solution
- Solubility: Water or organic solvents, depending on surface modification
- Surface modification: Hydrophilic stabilisers (for example, phosphonate or carboxyl PEGs, DMSA) for biocompatibility, or long-chain amines for use in organic solvents.
- Storage: at 4 ℃