Strongly Magnetic Iron/Iron Oxide Core-Shell Nanoparticles

Strongly Magnetic Iron-Iron Oxide Nanoparticles
Strongly Magnetic Iron-Iron Oxide Nanoparticles

At Boutiq, we have pioneered a novel synthesis for unique iron-iron oxide core-shell nanoparticles which exhibit strong magnetic behaviour. Most current magnetic nanoparticles use iron oxides, which show weaker magnetic behaviour than pure iron.

In comparison, the magnetisation of our Fe-FeOx NPs is up to 150 emug-1, which is at least double the 40-70 emug-1 reported for commercially available iron oxide. In addition, our Fe-FeOx nanoparticles are uniformly sized and are near ‘superparamagnetic’: with a small to zero coercivity they only show magnetic behaviour in a magnetic field.

As they can be made biocompatible with surface modification, they are ideal candidates for applications in MRI, drug delivery and magnetic hyperthermia. Please see our publications on these materials, including our research on application in MRI: where a T2 relaxivity of double current iron oxides results in improved negative contrast, specificity and sensitivity.

Unfortunately, due to our assignment of IP to Ferronova Pty Ltd of this technology, we will no longer be able to offer these materials for sale moving forward.

Relevant Publications

Using Magnetic Resonance Imaging to Evaluate Dendritic Cell-Based Vaccination. PLoS ONE 2013

Strongly Magnetic Iron Nanoparticles Improve the Diagnosis of Small Tumours….PLoS ONE 2013

Simple Synthesis and Functionalization of Iron Nanoparticles for MRI. Angewandte 2011

Synthesis and Stability of Highly Crystalline and Stable Fe/FeOx….ChemPlusChem 2012

Hot-injection synthesis of Fe/FeOx core/shell nanoparticles for T2 contrast….Chemm Comm. 2011

Example Specification Sheet

  • Material: Iron-Iron Oxide (Fe-FeOx) Core-Shell. Consists of iron metal (Fe) core with layer of iron oxide spinel shell.
  • Size: 10 to 15 nm
  • Standard deviation: < 3 nm
  • Shape: Spherical to near-cubic
  • Physical appearance: black solution
  • Solubility: Water or organic solvents, depending on surface modification
  • Surface modification: Hydrophilic stabilisers (for example, phosphonate or carboxyl PEGs, DMSA) for biocompatibility, or long-chain amines for use in organic solvents.
  • Storage: at 4 ℃

Size Analysis